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Acta cient. Soc. Venez. Bioanalistas Esp ; 13-15(1): 34-42, 2010-2012. tab, graf
Article in Spanish | LILACS | ID: lil-733431

ABSTRACT

El Síndrome Metabólico (SM), se puede definir como una serie de síntomas clínicos y biaoquímicos que se presentan, tanto en individuos obesos como delgados, aparentemente sanos. La importancia de SM radica en que las personas que lo padecen tienen mayor riesgo de desarrollar Enfermedades Cardiovasculares o Diabetes Mellitus tipo II (DM2). Determinar la incidencia de Síndrome Metabólico, sus factores de riesgo predominantes y la ralación existente con la insulina basal y post prandial en los pacientes que acudieron al Laboratorio Clínico Familia. Se estudiaron 100 pacientes de ambos sexos con edades comprendidas entre 13 a 71 años, que acudieron a Familia Laboratorios Clínicos. El diagnostico para síndrome metabólico fue definido de acuerdo a los criterios de la National Cholesterol Education Program (NECP)/Adult Treatment Panel III (ATP III). En esta investigación se observó un 75% de pacientes con estado nutricional alterado (44% obesos y 31% con sobrepeso) siendo estadísticamente significativo para la presencia de sobrepeso u obesidad respecto al estado nutricional normal (p<0,01). Se determinó una prevalencia para síndrome metabólico de 28% siendo el criterio más resaltante la circunferencia abdominal 96,4%, seguido de HDL-C bajo con 75% y triglicéridos altos en un 67,9%. Se midió la insulina basal obteniendo una prevalencia del 14% por encima del valor normal, donde solo el 7% fue diagnosticado con SM, el 35% presentó insulina post prandial elevada. Con los datos obtenidos se pudo observar que los valores de insulina postprandial, tomando como limite 60 µUI/ml, no se alteraron con respecto al número de criterios de diagnostico para SM, como tampoco hubo relación con la circunferencia abdominal, no se evidenció estadísticamente significativa entre la presencia de circunferencia abdominal por encima del límite establecido para cada sexo y la elevación de la insulina postprandial de 2 horas superiore a 60 µUI/ml., (p>0,05)...


Metabolic Syndrome (MS) can be defined as a series of clinical and biochemical symptoms that occur both in obese and lean apparently healthy. The importance of the SM is that people with the condition are at increased risk od developing cardiovascular disease and type II diabetes mellitus (T2DM). To determine the incidence of metabolic syndrome prevalen risk factors and the relationship with basal insulin and postprandial in patients presenting to the Family Clinical Laboratory. We studied 100 patients of both sexes aged 13-71 years, who attented Family Clinical Laboratory. The diagnosis for metabolic syndrome was defined according to the criteria of the National Cholesterol Education Program (NECP)/Adult Treatment Panel III (ATP III). In this survery found 75% of patients with altered nutritional status (44% obese and 31% overweight) were statisfically significant for presence of overweight or obese compared to normal nutritional status (p<0.01). The sero prevalence for metabolic syndrome of 28% being the most salient criterion waist circumference 96.4%, followed by low HDL-C by 75% and triglycerides by 67.9%. Basal insulin was measured by obtaining a prevalence of 14% above the normal value, where only 7% were diagnosed with MS, 35% had elevated postprandial insulin values, taking as limit 60 mUL/ml, were not altered with respect to the number of diagnostic criteria for MS, as there was no relationship with waist cirscumference, no evidence statiscally significant association between the presence of abdominal circumference above the limit established for each sex and elevated postprandial insulin over 2 hours 60 mUL/ml (p<0.05). This study was correlational, cross and not experimental, which found that the predominant risk for factor was by the abdominal circumference and overweight and obesity over the range for both sexes. No association between postprandial insulin, the prevalence of risk factors and waist circumference.


Subject(s)
Humans , Male , Adolescent , Adult , Female , Young Adult , Middle Aged , Nutritional Status , Receptor, Insulin/metabolism , Metabolic Syndrome/diagnosis , Blood Chemical Analysis , Endocrinology , Hematology
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